A mouthful of a title, I know, but I couldn't find a better way to articulate what I was aiming for. What workplace/hobby related interests do you have but you don't think your average person would give a crap about? Also why, to you personally, do you find these things interesting? For me, I do medicinal chemistry at university which I've mentioned before, but when I try to talk about it normally results in people's eyes glassing over and them looking at me as if they're trying to say "Oh my God why won't he stop?!" Personally I always try and keep superfluous detail out of my conversations with other people to keep them interested, but still the mention of a science subject seems to engender an almost automatic response of disinterest which is frustrating. As to me an example of what I specifically find interesting, currently I have a module which makes guest lecturers who are people employed in industry itself give me a talk for the day. Here's one example which I thought I'd share: So the company which did this research and are developing these drugs are called Vertex, I don't know if this information which I'm posting is readily available or not so I guess you'll have to take my word that it's the truth. First of all I'll start with some basic facts: Enzymes are catalysts that make chemical reactions go faster. Sometimes enzymes make a reaction occur which is normally vastly too slow to occur naturally. Kinase enzymes catalyse the phosphorylation, or transfer of a phosphate group, from one molecule to another as a means to transfer energy. From here on in the science is mostly done. So why may a kinase inhibition drug be important to treating cancer? Well as most people know cancer is an umbrella term for a variety of diseases all involving a single main theme: cancerous cells mutate out of control. So if you can stop cells from phosphorylating, or transferring energy to, targets responsible for activating this process by selectively inhibiting certain kinases then you can help to combat cancer. Why is this interesting? Well Vertex developed a drug to inhibit Aurora kinases, a kinase that took a vital role in mitosis - or cell division, of cancer cells. For the specific type of cancer they were treating the drug proved effective. However by pure serendipity the drug also happened to treat Philadelphia positive leukemia, a certain form of leukemia of which whose genes had begun to mutate against all current effective drugs to treat the disease. People who had Philadelphia positive leukemia were told categorically after sampling the few available drugs which often didn't prove effective that they were going to die. Because their drug had been designed for a different purpose, it was acting on the enzymes responsible for this leukemia much better than any other drugs currently on the market, as well as treating the form of cancer it had been designed for. I find this interesting because I find it unbelievable by pure chance that a drugs company had managed to give people hope when before there was none, but many people don't so it may just be me! Anyway post up similar examples of what you find interesting and yet few other people ever seem to.