There's no time limit for the main plot nor have I encountered a side quest with one - so don't worry if you hear that something is urgent (at least I never faced delay consequences). EDIT - there are 4 or 5 get this person (who becomes a temporary follower) minor quests in case of which if you don't take them where you promised ther'll leave. Also Doc Roberts' bank quest in Shrouded Hills has a time limit triggered after second converation (near the bank) with Doc. He gets mad if you don't enter the bank quickly. These are exceptions though.
That's cool then. The main thing is instead of spending 375g on train tickets, I prefer strolling my way around, kill and loot on my way... By the way, I'm a <<<<< Spiked Mace already! Cool! Cos the last object that represented me looked somewhat like something I might take offense to